Deuterium NMR study of amino acid coordination to chromium(III)

Journal Article · Wed Dec 17 04:00:00 EST 1986 · Inorg. Chem.; (United States)

DOI:https://doi.org/10.1021/ic00246a017· OSTI ID:6922307

Green, C A; Place, H; Willett, R D; Legg, J I

A series of bis(ethylenediamine)Cr(III)-amino acid complexes, synthesized with deuterium-labeled alanine, glycine, homoserine, leucine, methionine, phenylalanine, serine, and threonine, was characterized by /sup 2/H NMR spectroscopy. The spectra show that these bidentate-coordinated amino acid complexes decompose via monodentate species. In addition, the diastereomeric isomers of alanine and leucine can be distinguished in the spectra. This was confirmed by the isolation of one of the L-leucine isomers. The bis(1,3-propanediamine)Cr(III) complexes of glycine and alanine were also synthesized, and the NMR spectra of these complexes and ..cap alpha..-cis-(Cr(ethylenediaminediacetate)(glycinate)) show changes due to variation in the ligand complement. The crystal structure of ..cap alpha..-cis(Cr(ethylenediaminediacetate)(glycinate)) x 2H/sub 2/O (CrO/sub 6/N/sub 3/C/sub 8/H/sub 14/ x 2H/sub 2/O) was determined and supports the NMR observations. This complex crystallizes in the space group P2/sub 1//c of the monoclinic crystal system with a = 8.9231 (19) A, b = 10.1889 (22) A, c = 15.4180 (30) A, ..beta.. = 102.657 (17)/sup 0/, and Z = 4. An improved method for the synthesis of bis(diamine)Cr(III)-amino acid complexes is also reported. 24 references, 3 figures, 7 tables.

• Research Organization: Washington State Univ., Pullman
• OSTI ID: 6922307
• Journal Information: Inorg. Chem.; (United States), Journal Name: Inorg. Chem.; (United States) Vol. 25:26; ISSN INOCA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201* -- Chemical & Physicochemical Properties
400202 -- Isotope Effects
Isotope Exchange
& Isotope Separation
AMINO ACIDS
CARBOXYLIC ACIDS
CHROMIUM COMPLEXES
COMPLEXES
CRYSTAL STRUCTURE
DATA
DEUTERIUM
EXPERIMENTAL DATA
HYDROGEN ISOTOPES
INFORMATION
ISOTOPE EFFECTS
ISOTOPES
LIGHT NUCLEI
NMR SPECTRA
NUCLEI
NUMERICAL DATA
ODD-ODD NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
SPECTRA
STABLE ISOTOPES
TRANSITION ELEMENT COMPLEXES