Electron-microscopic study on the structure of indirect flight muscles in pupae of Drosophila melanogaster muscle mutant
Journal Article
·
· Russian Journal of Developmental Biology
OSTI ID:83472
We have analyzed the ultrastructure of indirect flight muscles in Drosophila pupae heterozygous for the mutation Mhc{sup M66}, which is a cold-sensitive allele of locus Mhc (Myosin heavy chain). We found that initially the differentiation of the muscle fiber in the mutant does not differ from that of the wild type. The first visible changes (loss of individual myosin protofibrils) appear in myofibrils reaching a certain size. Disintegration of contractile machinery progresses with the increase in the size of myofibrils. We discuss possible mechanisms of triggering and progression of these destructive processes during ontogenesis. 26 refs., 2 figs.
- OSTI ID:
- 83472
- Journal Information:
- Russian Journal of Developmental Biology, Journal Name: Russian Journal of Developmental Biology Journal Issue: 6 Vol. 25; ISSN RJDBE2; ISSN 1062-3604
- Country of Publication:
- United States
- Language:
- English
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