Eye-tracking dysfunctions in schizophrenic patients and their relatives

Journal Article · Thu Aug 01 04:00:00 EDT 1974 · Arch. Gen. Psychiatr.; (United States)

DOI:https://doi.org/10.1001/archpsyc.1974.01760140005001· OSTI ID:7368375

Holzman, P S; Proctor, L R; Levy, D L; Yasillo, N J; Meltzer, H Y; Hurt, S W

A simple test of smooth-pursuit eye movements disclosed a striking association between deviant eye tracking and clinically diagnosed schizophrenia. A high proportion of the schizophrenic patients' first-degree relatives who were not themselves clinically schizophrenic also showed deviant eye-tracking behavior. The relationship of poor eye tracking and schizophrenia is even stronger when specific psychological test evidence of thought disorder is used operationally to classify patients. The eye-tracking dysfunction may thus represent a genetic marker that can prove highly useful for studying the transmission of a vulnerability to schizophrenia. The findings suggest proprioceptive and interoceptive involvement in schizophrenic pathology. (auth)

• Research Organization: Univ. of Chicago
• OSTI ID: 7368375
• Journal Information: Arch. Gen. Psychiatr.; (United States), Journal Name: Arch. Gen. Psychiatr.; (United States) Vol. 31; ISSN ARGPA
• Country of Publication: United States
• Language: English

Related Subjects

550100* -- Behavioral Biology
59 BASIC BIOLOGICAL SCIENCES
BEHAVIOR
BIOLOGY
BODY
DIAGNOSTIC TECHNIQUES
DISEASES
EYES
GENETICS
MENTAL DISORDERS
NERVOUS SYSTEM DISEASES
ORGANS
SENSE ORGANS