Synthesis of DNA containing uracil (or 5-hydroxymethyluracil) during bacteriophage infection of Bacillus subtilis. Comprehensive report, August 1, 1973--July 31, 1976
The infection of Bacillus subtilis (whose DNA contains thymine) by viruses whose DNA contains uracil (PBS2 phage) or 5-hydroxymethyluracil (phi e phage) instead of thymine was studied. The goal was to learn how and why these unusual viruses synthesize DNA containing unusual bases and to gain insight into why thymine evolved for most natural DNAs. (auth)
- Research Organization:
- Michigan Univ., Ann Arbor (USA). Dept. of Biological Chemistry
- Sponsoring Organization:
- US Energy Research and Development Administration (ERDA)
- OSTI ID:
- 7354979
- Report Number(s):
- COO-2101-28
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550500* -- Metabolism
550700 -- Microbiology
59 BASIC BIOLOGICAL SCIENCES
AZINES
BACILLUS
BACILLUS SUBTILIS
BACTERIA
BACTERIOPHAGES
BIOLOGICAL EFFECTS
BIOSYNTHESIS
CHEMICAL COMPOSITION
DNA
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
INFECTIVITY
MICROORGANISMS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PARASITES
PYRIMIDINES
SYNTHESIS
THYMINE
URACILS
VIRUSES
550700 -- Microbiology
59 BASIC BIOLOGICAL SCIENCES
AZINES
BACILLUS
BACILLUS SUBTILIS
BACTERIA
BACTERIOPHAGES
BIOLOGICAL EFFECTS
BIOSYNTHESIS
CHEMICAL COMPOSITION
DNA
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
INFECTIVITY
MICROORGANISMS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PARASITES
PYRIMIDINES
SYNTHESIS
THYMINE
URACILS
VIRUSES