/sup 99m/Tc-diphosphonate bone imaging and uptake in healing rat extraction sockets

Journal Article · Sun Aug 01 04:00:00 EDT 1976 · J. Nucl. Med.; (United States)

OSTI ID:7352931

Lurie, A G; Matteson, S R

Clinically positive bone scans of the jaws may result from a variety of benign dental conditions. An experimental system for studying radionuclide imaging and uptake in the jaws of rats was developed. Sequential /sup 99m/Tc-diphosphonate bone scans and radionuclide uptake determinations were performed on rats after standardized extractions of their mandibular left first molars. Positive bone scans were seen 4 to 16 days after molar extraction, and increased radionuclide uptake was found in the healing extraction wounds 4 to 42 days after the extraction. Conventional radiography and histology fail to show unusual bony architecture in extraction sockets at such times. These results correlate with clinical findings in patients and suggest that human beings may have positive bone scans for several months after dental extraction.

• Research Organization: Univ. of Connecticut Health Center, Farmington
• OSTI ID: 7352931
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 17:8; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
560172* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Animals-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BODY
BONE TISSUES
CONNECTIVE TISSUE
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
HEALING
HOURS LIVING RADIOISOTOPES
INJURIES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
JAW
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORAL CAVITY
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RATS
RECOVERY
RODENTS
SCINTISCANNING
SKELETON
SKULL
TECHNETIUM 99
TECHNETIUM ISOTOPES
TEETH
TISSUES
UPTAKE
VERTEBRATES
WOUNDS
YEARS LIVING RADIOISOTOPES