Effect of pentagastrin, histalog, glucagon, secretin, and perchlorate on the gastric handling of /sup 99m/Tc pertechnetate in mice

Journal Article · Wed Sep 01 00:00:00 EDT 1976 · Radiology; (United States)

OSTI ID:7352930

Khettery, J; Effmann, E; Grand, R J; Treves, S

Pentagastrin, histalog, glucagon, secretin, and perchlorate were intravenously injected into mice in order to investigate the hormonal regulation of /sup 99m/Tc pertechnetate uptake by gastric mucosa. Pentagastrin significantly increased uptake; the effect of histalog was weaker. Secretin did not alter the uptake. Glucagon produced some diminution, and perchlorate significantly inhibited gastric uptake. Hormones may play a role in improving the sensitivity and specificity of diagnostic tests for Meckel's diverticulum.

• Research Organization: Harvard Medical School, Boston
• OSTI ID: 7352930
• Journal Information: Radiology; (United States), Vol. 120:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
GASTRIN
BIOLOGICAL EFFECTS
GLUCAGON
HORMONES
PERTECHNETATES
UPTAKE
SECRETIN
STOMACH
METABOLISM
TECHNETIUM 99
ISOMERIC NUCLEI
MICE
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
DIGESTIVE SYSTEM
GASTROINTESTINAL TRACT
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
OXYGEN COMPOUNDS
PEPTIDE HORMONES
PEPTIDES
POLYPEPTIDES
PROTEINS
RADIOISOTOPES
RODENTS
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TRANSITION ELEMENT COMPOUNDS
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560172* - Radiation Effects- Nuclide Kinetics & Toxicology- Animals- (-1987)