Mantle irradiation in Hodgkin's disease. An analysis of technique, tumor eradication, and complications
Conference
·
· Cancer; (United States)
OSTI ID:7349022
Analysis of the treatment and follow-up records of 377 Hodgkin's disease patients who received mantle irradiation but no planned chemotherapy reveals an overall supradiaphragmatic relapse rate of 21 percent. Complications of treatment included symptomatic pulmonary radiation reaction (20 percent), pericarditis (13 percent), Lhermitte's sign (15 percent), and thyroid dysfunction (13 percent). The addition of a subcarinal block after 2500 to 3500 rads and the use of the thin lung block technique in selected patients have reduced the incidence of pulmonary and pericardial complications to less than 5 percent without sacrificing local control. Further modifications in technique and treatment policy are discussed in terms of improving the therapeutic ratio.
- Research Organization:
- Stanford Univ. School of Medicine, CA
- OSTI ID:
- 7349022
- Conference Information:
- Journal Name: Cancer; (United States) Journal Volume: 37:6
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CARDIOVASCULAR SYSTEM
DISEASES
ENDOCRINE GLANDS
GLANDS
HEART
HODGKINS DISEASE
IRRADIATION PROCEDURES
LUNGS
LYMPHOMAS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PLANNING
RADIATION EFFECTS
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
SIDE EFFECTS
THERAPY
THYROID
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CARDIOVASCULAR SYSTEM
DISEASES
ENDOCRINE GLANDS
GLANDS
HEART
HODGKINS DISEASE
IRRADIATION PROCEDURES
LUNGS
LYMPHOMAS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PLANNING
RADIATION EFFECTS
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
SIDE EFFECTS
THERAPY
THYROID