Induction of radioresistance in Escherichia coli. [X radiation, uv radiation]
Journal Article
·
· Biophys. J.; (United States)
The effect of prior treatment by inducing agents on the radioresistance of cells of Escherichia coli has been studied. In order to separate the induction process from the radiation-damage process, cells were first treated with inducing agents such as ultraviolet light, ionizing radiation, or nalidixic acid, allowed to become induced by incubation for 50 min and then given rifampin to prevent further induction. They were then tested for radiation sensitivity. It was found that all strains tested except recA/sup -/, lex/sup -/, and recB/sup -/ showed very apparent protection. Induction by uv had the most effect and by nalidixic acid the least. The time course of development of protection was observed in one case: it is 50 percent established in 15 min. The absence of effect in recA/sup -/ and lex/sup -/ is explainable by the fact that these cells cannot be induced, for example, for prophage or the inducible inhibitor of post-irradiation DNA degradation. We suggest that the inducible inhibitor of postirradiation DNA degradation is one factor in a recovery system possessed by E. coli cells.
- Research Organization:
- Pennsylvania State Univ., University Park
- OSTI ID:
- 7347524
- Journal Information:
- Biophys. J.; (United States), Journal Name: Biophys. J.; (United States) Vol. 15:11; ISSN BIOJA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Induced radioresistance in four strains of Escherichia coli, two with lambda lysogens
Influence of the lambda prophage on the action of the inducible inhibitor of postirradiation DNA degradation
Basic aspects of radiation action on microorganisms. Progress report, April 1, 1976--June 30, 1977. [Escherichia coli, Pseudomonas, lambda phage, gamma and uv radiation]
Journal Article
·
Thu Jun 01 00:00:00 EDT 1978
· Biophys. J.; (United States)
·
OSTI ID:6845057
Influence of the lambda prophage on the action of the inducible inhibitor of postirradiation DNA degradation
Journal Article
·
Mon Sep 01 00:00:00 EDT 1975
· Radiat. Res., v. 63, no. 3, pp. 553-559
·
OSTI ID:4158388
Basic aspects of radiation action on microorganisms. Progress report, April 1, 1976--June 30, 1977. [Escherichia coli, Pseudomonas, lambda phage, gamma and uv radiation]
Technical Report
·
Fri Jul 01 00:00:00 EDT 1977
·
OSTI ID:7294542
Related Subjects
560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BACTERIA
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
ELECTROMAGNETIC RADIATION
ESCHERICHIA COLI
IONIZING RADIATIONS
MICROORGANISMS
RADIATION EFFECTS
RADIATIONS
RADIOSENSITIVITY
ULTRAVIOLET RADIATION
X RADIATION
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BACTERIA
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
ELECTROMAGNETIC RADIATION
ESCHERICHIA COLI
IONIZING RADIATIONS
MICROORGANISMS
RADIATION EFFECTS
RADIATIONS
RADIOSENSITIVITY
ULTRAVIOLET RADIATION
X RADIATION