Repair of sublethal and potentially lethal radiation damage by rat embryos exposed to gamma rays or helium ions

Conference · Wed Sep 01 04:00:00 EDT 1976 · Radiology; (United States)

OSTI ID:7339104

Ward, W F; Aceto, H Jr; Sandusky, M

Embryonic survival was examined in rats exposed to a 24-hour split-dose regimen of gamma rays or extended-Bragg-peak (EBP) helium ions on the fifth and sixth days of gestation. The data indicate that EBP helium ions, which are known to have a single-dose relative biological effectiveness (RBE) of 1.0, exhibit a split-dose RBE of 1.5 with respect to embryo killing. Using an experimental rat embryo system, delayed implantation, it was also noted that the embryocidal damage induced by EBP helium ions contains a smaller potentially lethal component than that induced by gamma rays.

• Research Organization: Northwestern Univ. Medical School, Chicago
• OSTI ID: 7339104
• Conference Information: Journal Name: Radiology; (United States) Journal Volume: 120:3
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
BRAGG CURVE
DIAGRAMS
ELECTROMAGNETIC RADIATION
EMBRYOS
FRACTIONATED IRRADIATION
GAMMA RADIATION
HELIUM IONS
INJURIES
IONIZING RADIATIONS
IRRADIATION
MAMMALS
RADIATION EFFECTS
RADIATION INJURIES
RADIATIONS
RATS
RBE
RECOVERY
REPAIR
RODENTS
VERTEBRATES