Effects of radiation therapy on growing long bones

Journal Article · Wed Dec 01 04:00:00 EST 1976 · Am. J. Roentgenol.; (United States)

DOI:https://doi.org/10.2214/ajr.127.6.935· OSTI ID:7338206

De Smet, A A; Kuhns, L R; Fayos, J V; Holt, J F

Characteristic radiographic changes were seen in six of 14 children who received radiation therapy to the epiphyseal plate of a long bone. These changes, which include metaphyseal sclerosis, metaphyseal fraying, and epiphyseal plate widening, resemble rickets. In three patients, these changes were followed by development of a broad metaphyseal band of increased density. The absence of metaphyseal changes may indicate sterilization of cartilage cells and may be predictive of significant limb shortening.

• Research Organization: Univ. of Michigan, Ann Arbor
• OSTI ID: 7338206
• Journal Information: Am. J. Roentgenol.; (United States), Journal Name: Am. J. Roentgenol.; (United States) Vol. 127:6; ISSN AJROA
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOMEDICAL RADIOGRAPHY
BODY
CHILDREN
DIAGNOSTIC TECHNIQUES
IONIZING RADIATIONS
MAMMALS
MAN
MEDICINE
NUCLEAR MEDICINE
ORGANS
PATIENTS
PRIMATES
RADIATION EFFECTS
RADIATIONS
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SKELETON
THERAPY
VERTEBRATES