Cardioversion and false positive technetium-99m stannous pyrophosphate myocardial scintigrams

Journal Article · Wed Sep 01 04:00:00 EDT 1976 · Circulation; (United States)

DOI:https://doi.org/10.1161/01.CIR.54.3.399· OSTI ID:7334032

Pugh, B R; Buja, L M; Parkey, R W; Poliner, L R; Stokely, E M; Bonte, F J; Willerson, J T

The present studies performed in experimental animals demonstrate that electrical direct current cardioversion can produce skeletal muscle damage and increased technetium-99m stannous pyrophosphate (/sup 99m/Tc-PYP) uptake; in exerimental animals the electricity damaged skeletal muscle shows necrosis with extensive calcium deposition. In addition, the frequent administration of high energy cardioversion produces myocardial necrosis with calcium deposition, increased /sup 99m/Tc-PYP myocardial uptake and a positive /sup 99m/Tc-PYP myocardial scintigram. The data indicate that, if diagnostic /sup 99m/Tc-PYP myocardial scintigraphy is contemplated after cardioversion, paddle placement should be slightly removed from the anteroposterior projection of the heart on the external chest wall to avoid possible subsequent confusion between increased myocardial and skeletal muscle uptake of /sup 99m/Tc-PYP. If multiple high energy cardioversion episodes are necessary, myocardial necrosis resulting from electrical injury may occur and be responsible for increased myocardial uptake of /sup 99m/Tc-PYP with a resultant positive /sup 99m/Tc-PYP myocardial scintigram.

• Research Organization: Univ. of Texas, Dallas
• OSTI ID: 7334032
• Journal Information: Circulation; (United States), Journal Name: Circulation; (United States) Vol. 54:3; ISSN CIRCA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
CURRENTS
DIAGNOSTIC TECHNIQUES
DISEASES
DOGS
ELECTRIC CURRENTS
ERRORS
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MUSCLES
MYOCARDIUM
NECROSIS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PATHOLOGICAL CHANGES
PHOSPHORUS COMPOUNDS
PYROPHOSPHATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM ISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES