Evaluation of the humoral immune response of children with low level lead exposure

Journal Article · Thu Jul 01 04:00:00 EDT 1976 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01753115· OSTI ID:7327713

Reigart, J R; Graber, C D

Twelve lead-exposed children, with evidence of metabolic impairment, and seven non-lead exposed children were examined for evidence of impairment of their immunological response. There were no differences between the control group and the lead exposed group with reference to complement levels, immunoglobulins, or anamnestic response to the tetanus toxoid antigen. It remains to be demonstrated whether or not there is deficient response to primary immunization, whether other antigens are more affected by lead, or whether impairment of humoral immune response requires a more serious degree of lead intoxication.

• Research Organization: Medical Univ. of South Carolina, Charleston
• OSTI ID: 7327713
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 16:1; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BLOOD SERUM
BODY BURDEN
CHILDREN
DISEASES
ELEMENTS
IMMUNITY
INFECTIOUS DISEASES
LEAD
MAMMALS
MAN
METABOLISM
METALS
PRIMATES
TETANUS
TOXOIDS
VERTEBRATES