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Blood flow in the small intestine of cat and man as analyzed by an inert gas washout technique

Journal Article · · Gastroenterology; (United States)
OSTI ID:7325962

Using a recently developed /sup 85/Kr-elimination technique, blood flow and flow distribution of the human small intestine have been investigated in patients during abdominal surgery. Total intestinal blood flow was estimated to be 38 +- 4 ml per min and 100 g of intestinal tissue (mean +- SE: n = 19), jejunal blood flow being slightly higher than ileal. In 14 of these patients muscularis blood flow was determined to be 21 +- 2 ml per min and 100 g of muscularis tissue and mucosal-submucosal blood flow was calculated to be 51 +- 6 ml per min and 100 g of mucosal-submucosal tissue. Seventy-five +-3 percent of total blood flow was distributed to the mucosa-submucosa and the remaining 25 +- 3 percent to the muscularis. It was demonstrated that an increasing fraction of flow was diverted to the mucosa-submucosa with enhanced total intestinal blood flow. The human gut exhibited great qualitative and quantitative circulatory similarities with the feline small intestine.

Research Organization:
Univ. of Goteborg
OSTI ID:
7325962
Journal Information:
Gastroenterology; (United States), Journal Name: Gastroenterology; (United States) Vol. 70:1; ISSN GASTA
Country of Publication:
United States
Language:
English