Quantifying the size of ischemic, infarcted, healing and/or scarred myocardium. Annual report, 30 Jun 1975--15 Apr 1976
Technical Report
·
OSTI ID:7312188
A portable gamma camera was procured, made operational and outfitted with a digital tape storage and retrieval system compatible with an IBM 370 computer for image enhancement and image subtraction. Preliminary results on processed tapes are very encouraging. Cyclotron production of Thallium-201 has progressed as anticipated and current yields of medically useful radiopharmaceutical average 22 mCi per week. Dual isotope imaging using Thallium-201 followed by (99m)Tc-diphosphonate or pyrophosphate has been performed in 35 patients with acute myocardial infarction. Image quality is excellent. Studies in dogs have shown advantages in use of (99m)Tc pyrophosphate compared to diphosphonate; that regional hypoxic myocardium simulates myocardial infarction with Thallium-201 but not with (99m)Tc diphosphonate or pyrophosphate; and that differences in image quality between (201)Tl and (99m)Tc EHDP may be explained in part by the severity and extent of cellular damage and the degree of perfusion abnormality in the microcirculation.
- Research Organization:
- Cincinnati Univ., OH (USA). Coll. of Medicine
- OSTI ID:
- 7312188
- Report Number(s):
- PB-262335
- Country of Publication:
- United States
- Language:
- English
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·
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·
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANEMIAS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DUAL-ISOTOPE SUBTRACTION TECHNIQUE
ELECTRON CAPTURE RADIOISOTOPES
HEART
HEAVY NUCLEI
HEMIC DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISCHEMIA
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MUSCLES
MYOCARDIAL INFARCTION
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
SYMPTOMS
TECHNETIUM 99
TECHNETIUM ISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
TRACER TECHNIQUES
YEARS LIVING RADIOISOTOPES
62 RADIOLOGY AND NUCLEAR MEDICINE
ANEMIAS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DUAL-ISOTOPE SUBTRACTION TECHNIQUE
ELECTRON CAPTURE RADIOISOTOPES
HEART
HEAVY NUCLEI
HEMIC DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISCHEMIA
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MUSCLES
MYOCARDIAL INFARCTION
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
SYMPTOMS
TECHNETIUM 99
TECHNETIUM ISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
TRACER TECHNIQUES
YEARS LIVING RADIOISOTOPES