Discussion of the combined effect of weightlessness and ionizing radiation on the mammalian body: morphological data. [Gamma radiation, rats]

Journal Article · Sat Jan 01 04:00:00 EST 1977 · Aviat., Space Environ. Med.; (United States)

OSTI ID:7312065

Portugalov, V V; Savina, E A; Kaplanskii, A S; Yakovleva, V I; Durnova, G N; Pankova, A S; Shvets, V N; Alekseev, E I; Katunyan, P I

The combined effect of weightlessness and ionizing radiation, from the /sup 137/Cs source at 800 rads for 24 h, on the animal body was studied. The morphological examination of organs and tissues of rats flown aboard the biosatellite Cosmos-690, kept in the ground-based simulation experiment, and kept in the vivarium, indicated prevalence of radiation-induced changes in both experimental groups of rats. An exposure of animals to space flight factors did not produce a substantial aggravation of radiation-induced effects. This is indicated by the lack of significant differences in the weight of testes, thymus, and spleen of flight and simulation rats. However, this exposure affected adversely the development of reparative processes in the hemopoietic tissue of bone marrow. Inflight irradiation aggravated weightlessness-induced changes. A combined effect of weightlessness and irradiation did not result in the summation of the effects exerted on skeletal muscles by either factor alone.

• Research Organization: Inst. of Biomedical Problems, Moscow
• OSTI ID: 7312065
• Journal Information: Aviat., Space Environ. Med.; (United States), Journal Name: Aviat., Space Environ. Med.; (United States) Vol. 48:1; ISSN ASEMC
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BONE MARROW
ELECTROMAGNETIC RADIATION
GAMMA RADIATION
GONADS
HEMATOPOIETIC SYSTEM
IONIZING RADIATIONS
LYMPHATIC SYSTEM
MALE GENITALS
MAMMALS
ORGANS
RADIATION EFFECTS
RADIATIONS
RADIOSENSITIVITY EFFECTS
RATS
RODENTS
SATELLITES
SPACE FLIGHT
SPLEEN
TESTES
THYMUS
TISSUES
VERTEBRATES
WEIGHT