Combined effect of space flight and radiation on skeletal muscles of rats

Journal Article · Tue Feb 01 04:00:00 EST 1977 · Aviat., Space Environ. Med.; (United States)

OSTI ID:6699446

Ilyina-Kakueva, E I; Portugalov, V V

Skeletal muscles of rats flown for 20.5 d aboard the biosatellite Cosmos-690 and irradiated with a dose of 800 rads on the 10th flight day were studied. The radiation exposure aggravated the severity of atrophic and dystrophic processes in m. soleus and atrophic process in m. gastrocnemius that developed under the conditions of weightlessness and hypokinesia. At the same time, an exposure to penetrating radiation did not affect the muscles where no flight-induced pathologies occurred. The radiation affected the pattern of reparation in those regions of the soleus muscle that developed pathology inflight, slowed down resorption of the connective tissue formed during the pathological process, and inhibited the course of the reparative process.

• Research Organization: Inst. of Biomedical Problems, Moscow
• OSTI ID: 6699446
• Journal Information: Aviat., Space Environ. Med.; (United States), Journal Name: Aviat., Space Environ. Med.; (United States) Vol. 48:2; ISSN ASEMC
• Country of Publication: United States
• Language: English

Related Subjects

550000 -- Biomedical Sciences
Basic Studies
560114* -- Radiation Effects on Biochemicals-- In Animals-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ATROPHY
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
BODY
CONNECTIVE TISSUE
DISEASES
MAMMALS
MUSCLES
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIATIONS
RATS
RECOVERY
REPAIR
RODENTS
SPACE FLIGHT
TISSUES
VERTEBRATES