Genetic evidence for the existence of partial replicas of T4 genomes inactivated by irradiation under ultraviolet light

Journal Article · Sun May 15 04:00:00 EDT 1977 · Virology; (United States)

DOI:https://doi.org/10.1016/0042-6822(77)90121-0· OSTI ID:7310886

Rayssiguier, C; Vigier, P R.R.

Multiplicity reactivation of uv-inactivated phages has been studied using two strains carrying a total of 35 markers well distributed along the entire length of the phage T4 genome. Analysis of the clone size distribution of all genotypes in single bursts of bacteria infected with only one phase of each parental type reveals the following two main features: the existence of partial replicas of damaged genomes that reassociate at a late stage in the infection process by recombining primarily at their extremities; and a repair mechanism involving interaction between the early replication products of a single damaged genome.

• Research Organization: Univ., Paris, Orsay
• OSTI ID: 7310886
• Journal Information: Virology; (United States), Journal Name: Virology; (United States) Vol. 78:2; ISSN VIRLA
• Country of Publication: United States
• Language: English

Related Subjects

550400 -- Genetics
560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BACTERIOPHAGES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
BIOLOGY
ELECTROMAGNETIC RADIATION
GENETICS
GENOTYPE
INACTIVATION
MICROORGANISMS
PARASITES
RADIATION EFFECTS
RADIATIONS
RECOVERY
REPAIR
ULTRAVIOLET RADIATION
VIRUSES