Differentiated thyroid carcinomas: treatment of distant metastases. [Long term study of sodium iodine-131 effect after surgery]
Conference
·
· Arch. Surg. (Chicago); (United States)
OSTI ID:7295890
During the 26-year period from 1947 to 1973, 333 patients with differentiated thyroid carcinomas were treated with sodium iodide I 131 post-operatively. Thirty-six of these (10.6 percent) had metastases to lung or bone or both. The mean age at the time of diagnosis was 36.1 years (range, 6 to 69 years). Mortality from thyroid carcinomas was 27.8 percent. Average follow-up interval from diagnosis was 19.8 years for those with papillary carinomas and lung metastases and 23.0 years for those with follicular carcinomas and lung metastases. Although seven of ten patients with bone metastases died, the five-year survival was 100 percent in this group. The average dose of sodium iodide I 131 was 383.2 millicuries for papillary distant metastases and 571.2 millicuries for follicular metastases. Total thyroidectomy prior to treatment of distant metastases with sodium iodide I 131 is important for successful management.
- Research Organization:
- Univ. of Michigan Medical Center, Ann Arbor
- OSTI ID:
- 7295890
- Conference Information:
- Journal Name: Arch. Surg. (Chicago); (United States) Journal Volume: 108
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550600* -- Medicine
560161 -- Radionuclide Effects
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& Toxicology-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL COMPOUNDS
BETA DECAY RADIOISOTOPES
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INORGANIC PHOSPHORS
INTERMEDIATE MASS NUCLEI
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NEOPLASMS
NUCLEAR MEDICINE
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RADIOACTIVE MATERIALS
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560161 -- Radionuclide Effects
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62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL COMPOUNDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
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DAYS LIVING RADIOISOTOPES
DISEASES
DRUGS
ENDOCRINE GLANDS
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HALIDES
HALOGEN COMPOUNDS
INORGANIC PHOSPHORS
INTERMEDIATE MASS NUCLEI
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LABELLED COMPOUNDS
MEDICINE
METASTASES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PHOSPHORS
RADIATION EFFECTS
RADIOACTIVE MATERIALS
RADIOISOTOPES
RADIOLOGY
RADIOPHARMACEUTICALS
RADIOTHERAPY
SODIUM COMPOUNDS
SODIUM IODIDES
SURGERY
THERAPY
THYROID
THYROIDECTOMY