Thyroid neoplasms after radiation therapy for adolescent acne vulgaris. [X radiation]

Journal Article · Sun Jan 01 00:00:00 EST 1978 · Arch. Dermatol.; (United States)

DOI:https://doi.org/10.1001/archderm.1978.01640130017004· OSTI ID:5038381

Paloyan, E; Lawrence, A M

There is a potential hazard of thyroid cancer after exposure to external irradiation for the treatment of adolescent acne vulgaris. We noted a 60% incidence of thyroid carcinoma among 20 patients with such a history, who were operated on for thyroid nodules during a five-year period. Eighty-three percent of the patients with carcinoma had either a follicular or a mixed papillary-follicular carcinoma; 17% had a papillary carcinoma; 33% had regional node metastases; none had evidence of distant metastases. The interval between radiation exposure and thyroidectomy ranged from nine to 41 years. This association of thyroid neoplasms and a prior history of radiation for acne vulgaris may be coincidental and therefore remains to be proved by retrospective surveys of large numbers of treated patients with appropriate controls.

• Research Organization: Loyola Univ. Stritch School of Medicine, Hines, IL
• OSTI ID: 5038381
• Journal Information: Arch. Dermatol.; (United States), Vol. 114:1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
NEOPLASMS
RADIOINDUCTION
RADIOTHERAPY
SIDE EFFECTS
THYROID
BIOLOGICAL RADIATION EFFECTS
HEALTH HAZARDS
METASTASES
PATIENTS
SKIN DISEASES
X RADIATION
BIOLOGICAL EFFECTS
BODY
DISEASES
ELECTROMAGNETIC RADIATION
ENDOCRINE GLANDS
GLANDS
HAZARDS
IONIZING RADIATIONS
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIATIONS
RADIOLOGY
THERAPY
560151* - Radiation Effects on Animals- Man