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Experimental studies on human health effects of air pollutants. III. Two-hour exposure to ozone alone and in combination with other pollutant gases

Journal Article · · Arch. Environ. Health; (United States)
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Adult male volunteers were exposed to ozone (O/sub 3/) at 0.25, 0.37, or 0.50 ppm, and to O/sub 3/ in combination with nitrogen dioxide (NO/sub 2/) and carbon monoxide (CO), with secondary stresses of heat, intermittent light exercise, and repeated exposure. Few important physiological changes, and only mild symptoms, were found with 0.25 ppm O/sub 3/, with 0.25 ppm O/sub 3/ plus 0.30 ppm NO/sub 2/, or when 30 ppm CO was added to the latter mixture. With 0.37 ppm O/sub 3/, more symptoms were present and some subjects developed definite decreases in pulmonary function. With 0.50 ppm O/sub 3/, most subjects had symptoms and about half showed substantial pulmonary function decrement. In reactive subjects exposed on two successive days, changes were usually greater the second day, indicating that effects of successive exposures were cumulative.

Research Organization:
Rancho Los Amigos Hospital, Downey, CA
OSTI ID:
7286100
Journal Information:
Arch. Environ. Health; (United States), Journal Name: Arch. Environ. Health; (United States) Vol. 30:8; ISSN AEHLA
Country of Publication:
United States
Language:
English

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Related Subjects

552000* -- Public Health
560306 -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
99 GENERAL AND MISCELLANEOUS
AIR POLLUTION
ANIMALS
BIOLOGICAL EFFECTS
CARBON COMPOUNDS
CARBON MONOXIDE
CARBON OXIDES
CHALCOGENIDES
DOSE-RESPONSE RELATIONSHIPS
INHALATION
INTAKE
MAMMALS
MAN
NITROGEN COMPOUNDS
NITROGEN DIOXIDE
NITROGEN OXIDES
OXIDES
OXYGEN COMPOUNDS
OZONE
PHOTOCHEMICAL OXIDANTS
POLLUTION
PRIMATES
RESPIRATORY SYSTEM
VERTEBRATES