Placental transport of lindane during early and late stages of gestation in rats

Journal Article · Tue Oct 01 04:00:00 EDT 1991 · Bulletin of Environmental Contamination and Toxicology; (United States)

DOI:https://doi.org/10.1007/BF01700938· OSTI ID:7278748

Khanna, R N; Kunwar, K; Gupta, R; Gupta, G S.D. ^[1]

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1. Industrial Toxicology Research Centre, Lucknow (India)

Lindane (gamma-isomer of hexachlorocyclohexane, gamma-HCH), an organochlorine pesticide, is widely used as an agricultural pesticide especially in developing countries. Human exposure is likely because of its use in some pharmaceutical preparations and in public health for pest control purpose. It has been detected in human milk and fat samples in India and in many developed countries. The accumulation of lindane over a long period in fat samples and its presence in milk suggests that the human fetus may be exposed to lindane at some time during gestation from the maternal tissue stores. The present study was, therefore, undertaken to determine the placental transfer of lindane in rats during early and late stages of gestation.

• OSTI ID: 7278748
• Journal Information: Bulletin of Environmental Contamination and Toxicology; (United States), Journal Name: Bulletin of Environmental Contamination and Toxicology; (United States) Vol. 47:4; ISSN 0007-4861; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADIPOSE TISSUE
ANIMAL TISSUES
ANIMALS
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CHLORINATED ALICYCLIC HYDROCARBONS
CONNECTIVE TISSUE
FETAL MEMBRANES
FOOD
HALOGENATED ALICYCLIC HYDROCARBONS
INSECTICIDES
LINDANE
MAMMALS
MATERIALS
MEMBRANE TRANSPORT
MEMBRANES
MILK
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
PESTICIDES
PLACENTA
PREGNANCY
PRENATAL EXPOSURE
RATS
RODENTS
TISSUES
VERTEBRATES