Effects of trace metals on the production of aflatoxins by Aspergillus parasiticus

Journal Article · Tue Jul 01 04:00:00 EDT 1975 · Appl. Microbiol.; (United States)

OSTI ID:7275945

Marsh, P B; Simpson, M E; Trucksess, M W

Certain metals added as salts to a defined basal culture medium influenced the level of aflatoxin production by Aspergillus parasiticus in the low micrograms-per-milliliter range of the added metal. In many cases no change or a relatively small change in mat weight and final pH of the medium accompanied this effect. With zinc at added levels of 0 to 10 ..mu..g/ml in the medium, aflatoxin increased 30-to 1,000-fold with increasing of zinc, whereas mat weight increased less than threefold. At 25 ..mu..g of added zinc per ml, aflatoxin decreased, but mat weight did not. At an added level of 25 ..mu..g or less of the metal per ml, salts of iron, manganese, copper, cadmium, trivalent chromium, silver, and mercury partly or completely inhibited aflatoxin production, without influencing mat weight.

• Research Organization: Agrcultural Research Service, Beltsville, MD
• OSTI ID: 7275945
• Journal Information: Appl. Microbiol.; (United States), Journal Name: Appl. Microbiol.; (United States) Vol. 30:1; ISSN APMBA
• Country of Publication: United States
• Language: English

Related Subjects

550700 -- Microbiology
560302* -- Chemicals Metabolism & Toxicology-- Microorganisms-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AFLATOXIN
BIOLOGICAL EFFECTS
BIOSYNTHESIS
CADMIUM
CHROMIUM
COPPER
ELEMENTS
IRON
MANGANESE
MERCURY
METALS
SILVER
SYNTHESIS
TOXICITY
TRANSITION ELEMENTS
ZINC