Influence of inoculum size of Aspergillus parasiticus spores on aflatoxin production

Journal Article · Mon Dec 01 04:00:00 EST 1980 · Appl. Environ. Microbiol.; (United States)

OSTI ID:6200076

Sharma, A; Behere, A G; Padwal-Desai, S R; Nadkarni, G B

The influence of the inoculum size on growth and aflatoxin production was examined in Aspergillus parasiticus (NRRL 3145) by using a synthetic medium. The reduction in the number of spores by 4 to 5 log cycles either by serial dilution or by gamma irradiation caused a two fold increase in the toxin production. The decrease in the inoculum size induced a lag in growth of the culture, though the final yield of the mycelium over the 28-day experimental period was the same. The maximal accumulation of aflatoxin was observed on day 14 of incubation. A transition from the biphasic to monophasic pattern in aflatoxin production could be correlated with the size of the inoculum. The enhanced toxin production from dilute inocula was similar to that obtained with the surviving fraction of the spores after gamma irradiation (0 to 150 krads).

• OSTI ID: 6200076
• Journal Information: Appl. Environ. Microbiol.; (United States), Journal Name: Appl. Environ. Microbiol.; (United States) Vol. 40:6; ISSN AEMID
• Country of Publication: United States
• Language: English

Related Subjects

550700 -- Microbiology
560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AFLATOXIN
ASPERGILLUS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOSYNTHESIS
ELECTROMAGNETIC RADIATION
FUNGI
GAMMA RADIATION
IONIZING RADIATIONS
MYCELIUM
PLANT TISSUES
PLANTS
RADIATION EFFECTS
RADIATIONS
SPORES
SYNTHESIS