Erythrocyte protoporphyrin test for occupational lead exposure

Journal Article · Sun Nov 30 23:00:00 EST 1975 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1975.10666785· OSTI ID:7265223

Tomokuni, K; Osaka, I; Igata, M

Determination of erythrocyte protoporphyrin levels was performed in workers who are occupationally exposed to lead. The level of erythrocyte protoporphyrin was easily measured with microsamples of blood by utilizing a fluorescent assay. The log of erythrocyte protoporphyrin level was closely correlated to blood lead level (r = .72) in lead-exposed workers. The erythrocyte protoporphyrin test is especially useful in the detection of mild increases in blood lead concentration under conditions of occupational exposure.

• Research Organization: Okayama Univ. Japan
• OSTI ID: 7265223
• Journal Information: Arch. Environ. Health; (United States), Journal Name: Arch. Environ. Health; (United States) Vol. 30:12; ISSN AEHLA
• Country of Publication: United States
• Language: English

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550200 -- Biochemistry
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY BURDEN
BODY FLUIDS
CARBOXYLIC ACIDS
CHLORINATED ALIPHATIC HYDROCARBONS
DISEASES
DOSE-RESPONSE RELATIONSHIPS
ELEMENTS
EMISSION SPECTROSCOPY
ENZYMES
ERYTHROCYTES
FLUORESCENCE SPECTROSCOPY
HALOGENATED ALIPHATIC HYDROCARBONS
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
INDUSTRY
LEAD
MAMMALS
MAN
MEASURING METHODS
METALS
MONITORING
OCCUPATIONAL DISEASES
ORGANIC ACIDS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC POLYMERS
PERSONNEL MONITORING
PIGMENTS
POLYMERS
POLYVINYLS
PORPHYRINS
PRIMATES
PROTOPORPHYRINS
PVC
RADIATION MONITORING
SPECTROSCOPY
TOXICITY
VERTEBRATES