Estimation of /sup 244/Cm intake by bioassay measurements following a contamination incident

Conference · Fri Jan 01 04:00:00 EST 1988

OSTI ID:7252576

Thein, M; Bogard, J S; Eckerman, K F

An employee was contaminated with radioactive material consisting primarily of /sup 244/Cm and /sup 246/Cm as a consequence of handling a curium nitrate solution at a reprocessing facility. In vivo gamma analysis and in vitro (urine and fecal) analysis were initiated soon after the incident. Further in vivo measurements were performed regularly through hour 528, and in vitro bioassay measurements were obtained through day 74. A sample of the curium solution from the workplace was obtained to confirm that the nitrate was the chemical form and to identify the curium isotopes present. The mass ratio of /sup 244/Cm:/sup 246/Cm was determined to be 91:7. Diethylenetriaminepentaacetate (DTPA) was administered on hours 33 and 71. Observed excretion rates were consistent with available information for curium in the literature. In this paper, the results of the in vivo and in vitro measurements are presented and intake estimates for the incident are developed using various excretion rate functions. 11 refs., 3 figs., 2 tabs.

• Research Organization: Oak Ridge National Lab., TN (USA)
• DOE Contract Number: AC05-84OR21400
• OSTI ID: 7252576
• Report Number(s): CONF-8805105-1; ON: DE88010140
• Country of Publication: United States
• Language: English

Related Subjects

560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE COMPOUNDS
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
ANIMALS
BIOASSAY
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY FLUIDS
CLEARANCE
CURIUM 244
CURIUM COMPOUNDS
CURIUM ISOTOPES
CURIUM NITRATES
EVEN-EVEN NUCLEI
EXCRETION
FECES
HEAVY NUCLEI
ISOTOPES
MAMMALS
MAN
MATERIALS
NITRATES
NITROGEN COMPOUNDS
NUCLEI
OCCUPATIONAL EXPOSURE
OXYGEN COMPOUNDS
POST-IRRADIATION THERAPY
PRIMATES
RADIOISOTOPES
RADIONUCLIDE KINETICS
THERAPY
TRANSPLUTONIUM COMPOUNDS
TRANSURANIUM COMPOUNDS
URINE
VERTEBRATES
WASTES
YEARS LIVING RADIOISOTOPES