Human T-cell lymphotropic virus type III infection in a cohort of homosexual men in New York City

Journal Article · Fri Apr 25 00:00:00 EST 1986 · JAMA, J. Am. Med. Assoc.; (United States)

DOI:https://doi.org/10.1001/jama.1986.03370160065028· OSTI ID:7245962

Stevens, C E; Taylor, P E; Zang, E A; Morrison, J M; Harley, E J; de Cordoba, S R; Bacino, C; Ting, R C; Bodner, A J; Sarngadharan, M G; Gallo, R C

Using blood samples collected since 1978, the authors investigated the epidemiology of human T-cell lymphotropic virus type III (HTLV-III), the etiologic agent of the acquired immunodeficiency syndrome, in a group of 378 homosexually active men who have resided in New York City since the acquire immunodeficiency syndrome epidemic began. The anti-HTLV-III prevalence was 6.6% in sera from 1978 or 1979, and the subsequent annual incidence of seroconversion among susceptible men ranged between 5.5% and 10.6%. The highest incidences were in recent years, even though these men reported a decrease in their sexual activity during this time. These data demonstrate the continuing risk of HTLV-III infections in the homosexual population studied and emphasize the need for more effective prevention of transmission. The year during which antibody was first present was the only factor identified that was associated with altered cell-mediated immunity in antibody-positive men.

• Research Organization: New York Blood Center, NY
• OSTI ID: 7245962
• Journal Information: JAMA, J. Am. Med. Assoc.; (United States), Vol. 255:16
• Country of Publication: United States
• Language: English

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