Scintigraphic demonstration of abscesses with radioactive gallium labeled leukocytes
Journal Article
·
· Surg. Gynecol. Obstet.; (United States)
OSTI ID:7245633
Autologous peripheral blood leukocytes, labeled in vitro with /sup 67/Ga citrate, have been studied in 20 patients as a radioactive carrier for the scintigraphic visualization of septic inflammatory areas. /sup 67/Ga citrate was added to venous whole blood; following incubation, the blood was centrifuged, and the packed cells were reinfused. Scintiscans were obtained four and 24 hours later. The inflammatory process was demonstrated in nine of nine patients with confirmed sepsis. Eleven patients without sepsis had normal scans. There were no false-negative scans and one false-positive scan. The selective accumulation of the gallium labeled leukocytes in areas of septic inflammation was sufficient to allow scintigraphic demonstration of the inflammatory area.
- Research Organization:
- Harvard Medical School, Boston
- OSTI ID:
- 7245633
- Journal Information:
- Surg. Gynecol. Obstet.; (United States), Journal Name: Surg. Gynecol. Obstet.; (United States) Vol. 141:3; ISSN SGOBA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ABSCESSES
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM 67
GALLIUM ISOTOPES
INFLAMMATION
INTERMEDIATE MASS NUCLEI
ISOTOPES
LABELLED COMPOUNDS
LEUKOCYTES
NUCLEI
ODD-EVEN NUCLEI
PATHOLOGICAL CHANGES
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
TISSUES
62 RADIOLOGY AND NUCLEAR MEDICINE
ABSCESSES
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM 67
GALLIUM ISOTOPES
INFLAMMATION
INTERMEDIATE MASS NUCLEI
ISOTOPES
LABELLED COMPOUNDS
LEUKOCYTES
NUCLEI
ODD-EVEN NUCLEI
PATHOLOGICAL CHANGES
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
TISSUES