Chronic effects of mercuric chloride ingestion on rat adrenocortical function

Journal Article · Fri Sep 01 04:00:00 EDT 1989 · Bulletin of Environmental Contamination and Toxicology; (USA)

DOI:https://doi.org/10.1007/BF01701886· OSTI ID:7244223

Agrawal, R; Chansouria, J P.N. ^[1]

---

1. Banaras Hindu Univ., Varanasi (India)

Mercurial contamination of environment has increased. Mercury accumulates in various organs and adversely affects their functions. Some of the most prominent toxic effects of inorganic mercury compounds include neurotoxicity, hepatotoxicity and nephrotoxicity. Besides this, mercury has also been reported to affect various endocrine glands like pituitary, thyroid, gonadal and adrenal glands. There have been no reports on the toxic effects of chronic oral administration of varying doses of mercuric chloride on adrenocortical function in albino rats. The present work was undertaken to study the adrenocortical response to chronic oral administration of mercuric chloride of varying dose and duration in albino rats.

• OSTI ID: 7244223
• Journal Information: Bulletin of Environmental Contamination and Toxicology; (USA), Journal Name: Bulletin of Environmental Contamination and Toxicology; (USA) Vol. 43:3; ISSN 0007-4861; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADRENAL GLANDS
ADRENAL HORMONES
ANIMALS
BIOASSAY
BIOCHEMISTRY
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BLOOD PLASMA
BODY
BODY FLUIDS
CHEMISTRY
CHLORIDES
CHLORINE COMPOUNDS
CORTICOSTEROIDS
CORTICOSTERONE
DOSE-RESPONSE RELATIONSHIPS
ENDOCRINE GLANDS
GLANDS
GLUCOCORTICOIDS
HALIDES
HALOGEN COMPOUNDS
HYDROXY COMPOUNDS
INGESTION
INTAKE
KETONES
MAMMALS
MATERIALS
MERCURY CHLORIDES
MERCURY COMPOUNDS
MERCURY HALIDES
ORGANIC COMPOUNDS
ORGANS
PREGNANES
RATS
RODENTS
STEROIDS
VERTEBRATES