Scintigraphy of sacroliac joints in acute anterior uveitis. A study of thirty patients

Journal Article · Mon Nov 01 00:00:00 EST 1976 · Ann. Intern. Med.; (United States)

DOI:https://doi.org/10.7326/0003-4819-85-5-606· OSTI ID:7226302

Russell, A S; Lentle, B C; Percy, J S; Jackson, F I

HLA-B27 is a transplantation antigen found in a high proportion of patients with ankylosing spondylitis. Recently, an association has been shown to exist between HLA-B27 and acute uveitis, even in the absence of ankylosing spondylitis. We have examined the HLA antigen profile of 45 patients with acute nongranulomatous anterior uveitis and have confirmed this relation. In addition, using 90m technetium stannous pyrophosphate we have been able to demonstrate abnormal bone scan in 19 of 30 patients studied. Such abnormalities are limited to the sacroiliac joints but are otherwise the same as those seen in overt ankylosing spondylitis. Seven of the 19 patients did not have HLA-B27. These factors suggest that acute anterior uveitis may often represent a manifestation of a spondylitic diathesis even in the complete absence of any suggestive symptomatic or radiologic change and, in some cases, even through the antigenic marker HLA-B27 may be absent.

• OSTI ID: 7226302
• Journal Information: Ann. Intern. Med.; (United States), Vol. 85:5
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BONE JOINTS
SCINTISCANNING
SKELETAL DISEASES
DIAGNOSIS
TECHNETIUM 99
ANTIGENS
IMMUNOLOGY
ISOMERIC NUCLEI
PATIENTS
PYROPHOSPHATES
SPONDYLITIS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PHOSPHORUS COMPOUNDS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SKELETON
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics