Scintigraphic investigation of sacroiliac disease. [/sup 99//super m/Tc tracer technique]

Journal Article · Wed Jun 01 00:00:00 EDT 1977 · J. Nucl. Med.; (United States)

OSTI ID:7142913

Lentle, B C; Russell, A S; Percy, J S; Jackson, F I

Bone scintigraphs obtained with both technetium-99m polyphosphate and technetium-99m pyrophosphate have been abnormal at the sacroiliac joints of 44 patients with definite ankylosing spondylitis (AS). Because of the normal registration of the sacroiliac joints on bone scintigraphy, it has been necessary to develop a profile-scan technique to quantify the abnormality that proves to be significantly different from the normal finding. In 17 patients with a strong clinical suspicion of AS but normal radiographs, the sacroiliac joints have frequently been abnormal. This finding is meaningful because there is a common occurrence in this group of the histocompatibility antigen HL A-B27, known to be a marker of AS. We also note the frequency of abnormal sacroiliac scintigrams in 26 patients with rheumatoid arthritis and in a group of other diseases--Crohn's disease, uveitis, psoriasis, ulcerative colitis, and Reiters' disease--all of which share some of the manifestations of AS.

• Research Organization: Univ. of Alberta, Edmonton
• OSTI ID: 7142913
• Journal Information: J. Nucl. Med.; (United States), Vol. 18:6
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BONE JOINTS
SCINTISCANNING
RHEUMATIC DISEASES
DIAGNOSIS
SPONDYLITIS
TECHNETIUM 99
ISOMERIC NUCLEI
PATIENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SKELETAL DISEASES
SKELETON
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics