Effect of ammonia partial pressure on the sensitivities for oxygenated compounds in ammonia chemical ionization mass spectrometry

Journal Article · Sun Nov 30 23:00:00 EST 1986 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00127a003· OSTI ID:7224449

Rudewicz, P; Munson, B

The sensitivities for monofunctional oxygenated compounds with proton affinities of 180-204 kcal/mol (alcohols, ketones, ethers, and esters) are very low under chemical ionization conditions with pure NH/sub 3/ at 0.5 torr and 180 /sub 0/C. The sensitivities of these compounds increase with decreasing partial pressure of NH/sub 3/ at a constant temperature and total pressure. The sensitivities of bifunctional compounds having proton affinities similar to that of NH/sub 3/ are not affected by the partial pressure of NH/sub 3/. These observations may be explained by a ligand-switching reaction for the monofunctional compounds and a solvation reaction for the bifunctional species.

• Research Organization: Univ. of Delaware, Newark
• OSTI ID: 7224449
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 58:14; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
400201 -- Chemical & Physicochemical Properties
ALCOHOLS
AMMONIA
CHEMICAL ANALYSIS
DATA
ESTERS
ETHERS
EXPERIMENTAL DATA
HIGH TEMPERATURE
HYDRIDES
HYDROGEN COMPOUNDS
HYDROXY COMPOUNDS
INFORMATION
KETONES
LIGANDS
MASS SPECTROSCOPY
MEDIUM VACUUM
NITROGEN COMPOUNDS
NITROGEN HYDRIDES
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PARTIAL PRESSURE
PRESSURE DEPENDENCE
QUANTITATIVE CHEMICAL ANALYSIS
RESOLUTION
SENSITIVITY
SPECTROSCOPY