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Neutral reactions in gas chromatography/chemical ionization mass spectrometry. [Ammonia and carbonyl compounds]

Journal Article · · Anal. Chem.; (United States)
DOI:https://doi.org/10.1021/ac00281a004· OSTI ID:5525640

The use of NH/sub 3/ as a carrier gas and as a reagent gas produces neutral reactions between NH/sub 3/ and carbonyl compounds to give basic products which are detected by NH/sub 3/ chemical ionization (CI) in the mass spectrometer. Reactions are observed with aldehydes and ketones but not alcohols, ethers, or esters. Postcolumn addition of NH/sub 3/ or CH/sub 3/NH/sub 2/ also gives neutral products which can be detected by NH/sub 3/ CI. On-column reactions are observed with carbonyl compounds by the injection of an amine immediately after the introduction of the sample. On-column reactions are also observed by adding acetone or acetic anhydride to a mixture of amines. 19 references, 5 figures.

Research Organization:
Univ. of Delaware, Newark
OSTI ID:
5525640
Journal Information:
Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 57:4; ISSN ANCHA
Country of Publication:
United States
Language:
English