Stable radiometal antibody immunoconjugates

Patent · Tue Aug 02 00:00:00 EDT 1994

OSTI ID:7199488

Mease, R C; Srivastava, S C; Gestin, J F

The present invention relates to new rigid chelating structures, to methods for preparing these materials, and to their use in preparing radiometal labeled immunoconjugates. These new chelates include cyclohexyl EDTA monohydride, the trans forms of cyclohexyl DTPA and TTHA, and derivatives of these cyclohexyl polyaminocarboxylate materials. No Drawings

• DOE Contract Number: AC02-76CH00016
• Assignee: Associated Universities, Inc., Washington, DC (United States)
• Patent Number(s): US 5334729; A
• Application Number: PPN: US 7-787244
• OSTI ID: 7199488
• Resource Relation: Patent File Date: 4 Nov 1991
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CHELATING AGENTS
CHEMICAL PREPARATION
RADIOPHARMACEUTICALS
RADIOIMMUNOASSAY
USES
BIOASSAY
DIAGNOSTIC TECHNIQUES
DRUGS
IMMUNOASSAY
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
RADIOASSAY
RADIOIMMUNODETECTION
SYNTHESIS
TRACER TECHNIQUES
550601* - Medicine- Unsealed Radionuclides in Diagnostics