Ultrastructural effects of acute tetraethyllead poisoning on nerve cells of the rabbit brain
Journal Article
·
· Environ. Res.; (United States)
A study of the ultrastructural alterations of nerve cell components in specific areas of the brain of the rabbit after acute poisoning with tetraethyllead (TEL). A single dose of 100 mg/kg of TEL caused neurological disorders such as convulsions after a latency of 12 to 18 h. An electron microscopic study revealed that the nerve cells of the areas investigated contained different stages of degenerative changes not demonstrated by light microscopy. These appear to be dependent on location and antedate the neurological disorders. The cytopathogenesis is discussed in the light of these findings and available biochemical data. (CIS Abstract Vol. 2)
- OSTI ID:
- 7196748
- Journal Information:
- Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 8:1; ISSN ENVRA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
02 PETROLEUM
020600 -- Petroleum-- Health & Safety
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGY
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CYTOLOGY
DISEASES
ELEMENTS
HAZARDS
HEALTH HAZARDS
LEAD
LEAD COMPOUNDS
MAMMALS
MEDICINE
METALS
MORPHOLOGICAL CHANGES
NERVE CELLS
NERVOUS SYSTEM
NEUROLOGY
ORGANIC COMPOUNDS
ORGANOMETALLIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
RABBITS
SOMATIC CELLS
TEL
ULTRASTRUCTURAL CHANGES
VERTEBRATES
020600 -- Petroleum-- Health & Safety
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGY
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CYTOLOGY
DISEASES
ELEMENTS
HAZARDS
HEALTH HAZARDS
LEAD
LEAD COMPOUNDS
MAMMALS
MEDICINE
METALS
MORPHOLOGICAL CHANGES
NERVE CELLS
NERVOUS SYSTEM
NEUROLOGY
ORGANIC COMPOUNDS
ORGANOMETALLIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
RABBITS
SOMATIC CELLS
TEL
ULTRASTRUCTURAL CHANGES
VERTEBRATES