Ga-67 SPECT before and after treatment of lymphoma

Journal Article · Tue May 01 04:00:00 EDT 1990 · Radiology; (USA)

DOI:https://doi.org/10.1148/radiology.175.2.2183289· OSTI ID:7192830

Front, D; Israel, O; Epelbaum, R; Ben Haim, S; Sapir, E E; Jerushalmi, J; Kolodny, G M; Robinson, E ^[1]

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1. Rambam Medical Center, Haifa (Israel)

The results of planar and single photon emission computed tomography (SPECT) gallium-67 scintigraphy performed before and after treatment were compared in 77 patients with lymphoma at 240 sites. Before treatment, the sensitivity of planar scintigraphy was 78% and the specificity was 97%; after treatment, 84% and 96%, respectively. Before treatment, SPECT had a sensitivity of 85% and a specificity of 98%; after treatment, 92% and 99%, respectively. In addition, SPECT allowed better anatomical localization and showed the entire extent of lesions at 36 sites. SPECT was of special value after treatment in excluding disease at 16 sites with residual masses seen at computed tomography (CT). Long-term follow-up in these patients showed that their condition was in complete remission and that the CT appearance of a residual mass does not always mean residual cancer. Thus, Ga-67 SPECT is a suitable imaging technique for monitoring the response of lymphoma to treatment.

• OSTI ID: 7192830
• Journal Information: Radiology; (USA), Journal Name: Radiology; (USA) Vol. 175:2; ISSN RADLA; ISSN 0033-8419
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
GALLIUM 67
GALLIUM ISOTOPES
IMMUNE SYSTEM DISEASES
INTERMEDIATE MASS NUCLEI
ISOTOPES
LYMPHOMAS
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SENSITIVITY ANALYSIS
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
TOMOGRAPHY