Chloracne. Clinical manifestations and etiology

Journal Article · Mon Jan 01 04:00:00 EST 1990 · Dermatologic Clinics; (USA)

OSTI ID:7189498

Zugerman, C ^[1]

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1. Northwestern Univ., Chicago, IL (USA)

Chloracne is a rare but important acneiform eruption often associated with the ingestion of chlorinated phenolic agents such as dioxins with subsequent toxicity from these chemicals. Clinically, chloracne can be distinguished from acne vulgaris by the distribution and appearance of the lesions and by taking a detailed history. In some instances, it may be associated with particularly xerotic skin, pigmentation, follicular hyperkeratosis, conjunctivitis, and actinic elastosis. Histologically, the primary lesion is a follicular plug containing keratinous material. Chloracne is difficult if not impossible to treat adequately and once present, may persist for years. Consequently, good hygiene, safe manufacturing processes so that no inhalation or skin contact is possible, and the elimination of atmospheric contamination are all necessary in the prevention of this potentially debilitating disease.34 references.

• OSTI ID: 7189498
• Journal Information: Dermatologic Clinics; (USA), Journal Name: Dermatologic Clinics; (USA) Vol. 8:1; ISSN 0733-8635; ISSN DRMCD
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AROMATICS
CHLORINATED AROMATIC HYDROCARBONS
DIOXIN
DISEASES
DOCUMENT TYPES
ENVIRONMENTAL EXPOSURE
HALOGENATED AROMATIC HYDROCARBONS
HETEROCYCLIC COMPOUNDS
MAMMALS
MAN
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PRIMATES
REVIEWS
SKIN DISEASES
TOXICITY
VERTEBRATES