Ion trap mass spectrometry using high-pressure ionization

Journal Article · Fri Jul 15 04:00:00 EDT 1994 · Analytical Chemistry (Washington); (United States)

DOI:https://doi.org/10.1021/ac00086a001· OSTI ID:7179757

McLuckey, S A; Van Berkel, G J; Goeringer, D E ^[1]; Glish, G L ^[2]

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1. Oak Ridge National Lab., TN (United States)
2. Univ. of North Carolina, Chapel Hill, NC (United States)

Given the preceding discussion in Part 1 of this series on the use of ion injection/quadrupole ion trap MS, it should be apparent that the ion trap may or may not be an appropriate mass analyzer for a given analytical problem, depending on the relative importance of the mass analyzer characteristics. Ion sources operated at high pressures, however, are natural candidates for coupling with a quadrupole ion trap because of pumping requirements and because ion injection efficiencies are highest for ions with low kinetic energy. The latter characteristic obviates the electrical isolation challenges associated with certain techniques, such as coupling high-pressure ionization sources with sector mass spectrometers. Many high-pressure ion sources are used with MS. In recent years, several of these have been coupled with the ion trap to address analytical challenges in both organic and inorganic MS. In this article, we review this work briefly, drawing from our own experiences with atmospheric sampling glow discharge ionization (ASGDI), a form of ionization that occurs at [approximately] 1 torr, and electrospray (ES), an atmospheric pressure technique. Our discussion is divided into these two pressure regimes and includes descriptions of organic and inorganic applications. 50 refs., 5 figs.

• DOE Contract Number: AC05-84OR21400
• OSTI ID: 7179757
• Journal Information: Analytical Chemistry (Washington); (United States), Journal Name: Analytical Chemistry (Washington); (United States) Vol. 66:14; ISSN 0003-2700; ISSN ANCHAM
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
400201 -- Chemical & Physicochemical Properties
CHARGED PARTICLES
EVALUATION
HIGH PRESSURE
IONIZATION
IONS
MASS SPECTROSCOPY
MULTIPOLES
QUADRUPOLES
SPECTROSCOPY
TRAPPING