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Synthesis of O,O,S-trialkyl phosphorothioites

Journal Article · · J. Gen. Chem. USSR (Engl. Transl.); (United States)
OSTI ID:7169699

The authors have developed a convenient method for the preparation of the O,O,S-trialkyl phosphorothioites consisting in the phosphorylation of 1-butanethiol, ..cap alpha..-toluenethiol, and ethyl mercaptoacetate with diethyl 1-methyl-3-oxo-1-butenyl phosphite. The phosphorylation of the thiols was conducted over a period of 4 days, and the yields of the O,O,S-trialkyl phosphorothioites attained 66%. The structures of the compounds synthesized were confirmed by their /sup 1/H and /sup 31/P NMR spectra.

Research Organization:
A. E. Arbuzov Institute of Organic and Physical Chemistry (USSR)
OSTI ID:
7169699
Journal Information:
J. Gen. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Gen. Chem. USSR (Engl. Transl.); (United States) Vol. 57:6; ISSN JGCHA
Country of Publication:
United States
Language:
English