Assignment of the gene for the cytochrome c[sub 1] subunit of the mitochondrial cytochrome bc[sub 1] complex (CYC1) to human chromosome 8q24. 3
Journal Article
·
· Genomics; (United States)
- Queens's Univ., Kingston (Canada)
- Univ. of Nagoya (Japan)
- McGill Univ., Montreal (Canada)
Cytochrome c[sub 1] is a subunit of the cytochrome bc[sub 1] complex (Complex III) of the mitochondrial electron transfer chain. Complex III, which mediates electron transfer for ubiquinol to cytochrome c, consists of 10-11 subunits:core proteins I and II, cytochromes b and c[sub 1], the Rieske iron-sulfur protein, the ubiquinone-binding protein, the hinge protein, and 3-4 subunits of low molecular weight. The human ubiquinone-binding protein and the cytochrome c[sub 1] subunit have both been assigned to human chromosome 8 by somatic cell hybrid mapping. In this study, the authors used in situ hybridization to confirm the localization of the cytochrome c[sub 1] gene to chromosome 8 and to assign it regionally to q24.3. 8 refs., 1 fig.
- OSTI ID:
- 7160440
- Journal Information:
- Genomics; (United States), Journal Name: Genomics; (United States) Vol. 19:2; ISSN GNMCEP; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
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