Synthesis of 2-carbethoxybenzofuran derivatives

Journal Article · Tue Dec 01 04:00:00 EST 1987 · Chem. Heterocycl. Compd. (Engl. Transl.); (United States)

DOI:https://doi.org/10.1007/BF00486904· OSTI ID:7160072

Prewysz-Kwinto, A

A mixture of 3-formyl and 3-acetoxymethyl derivatives is formed in the oxidation of 2-carbethoxy-3-methyl-7-ethylbenzofuran with selenium dioxide. Reduction with lithium aluminum hydride gives 2,3-dihydroxymethyl derivatives, which are converted to 2,3-diformyl derivatives by successive oxidation. A number of derivatives of 3-methyl-7-ethylbenzofurancarboxylic acid were obtained. The PMR spectra of solutions of the compounds in CDCl/sub 3/ were recorded with a Tesla B-487 spectrometer (80 Hz) with hexamethyldisiloxane (HMDS) as the internal standard. The IR spectra of KBr pellets of the compounds were obtained with a UR-10 spectrometer.

• Research Organization: N. Copernicus Univ., Torun (Poland)
• OSTI ID: 7160072
• Journal Information: Chem. Heterocycl. Compd. (Engl. Transl.); (United States), Journal Name: Chem. Heterocycl. Compd. (Engl. Transl.); (United States) Vol. 23:6; ISSN CHCCA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201* -- Chemical & Physicochemical Properties
ACETONE
ALKALI METAL COMPOUNDS
ALUMINIUM COMPOUNDS
ALUMINIUM HYDRIDES
BENZOFURANS
CARBOXYLIC ACID ESTERS
CATALYTIC EFFECTS
CHALCOGENIDES
CHEMICAL REACTIONS
CHEMICAL SHIFT
CHLORINATED ALIPHATIC HYDROCARBONS
CHLOROFORM
DEUTERIUM COMPOUNDS
ESTERS
FURANS
HALOGENATED ALIPHATIC HYDROCARBONS
HETEROCYCLIC COMPOUNDS
HYDRIDES
HYDROGEN COMPOUNDS
INFRARED SPECTRA
ISOTOPE EFFECTS
KETONES
LITHIUM COMPOUNDS
LITHIUM HYDRIDES
NMR SPECTRA
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
OXIDATION
OXIDES
OXYGEN COMPOUNDS
REDOX POTENTIAL
REDUCTION
SELENIUM COMPOUNDS
SELENIUM OXIDES
SPECTRA
SYNTHESIS