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Method for microbeam radiation therapy

Patent ·
OSTI ID:7159544
A method is disclosed of performing radiation therapy on a patient, involving exposing a target, usually a tumor, to a therapeutic dose of high energy electromagnetic radiation, preferably X-ray radiation. The dose is in the form of at least two non-overlapping microbeams of radiation, each microbeam having a width of less than about 1 millimeter. Target tissue exposed to the microbeams receives a radiation dose during the exposure that exceeds the maximum dose that such tissue can survive. Non-target tissue between the microbeams receives a dose of radiation below the threshold amount of radiation that can be survived by the tissue, and thereby permits the non-target tissue to regenerate. The microbeams may be directed at the target from one direction, or from more than one direction in which case the microbeams overlap within the target tissue enhancing the lethal effect of the irradiation while sparing the surrounding healthy tissue. No Drawings
DOE Contract Number:
AC02-76CH00016
Assignee:
Dept. of Energy, Washington, DC (United States)
Patent Number(s):
A; US 5339347
Application Number:
PPN: US 8-052927
OSTI ID:
7159544
Country of Publication:
United States
Language:
English

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