Retrograde transport of (/sup 3/H)-D-aspartate label by cochlear and vestibular efferent neurons
Journal Article
·
· Am. J. Otolaryngol.; (United States)
(/sup 3/H)-D-aspartic acid was injected into the inner ear of rats. After a six hour survival time, labeled cells were found at all locations known to contain efferent cochlear or vestibular neurons. Most labeled neurons were found in the ipsilateral lateral superior olivary nucleus (LSO), although both ventral nuclei of the trapezoid body (VTB), group E, and the caudal pontine reticular nucleus (CPR) just adjacent to the ascending limb of the facial nerve also contained labeled cells. Because not all efferent neurons in the rat could be previously shown to be cholinergic, aspartate and glutamate are efferent transmitter candidates.
- Research Organization:
- Univ. of British Columbia, Vancouver (Canada)
- OSTI ID:
- 7152541
- Journal Information:
- Am. J. Otolaryngol.; (United States), Vol. 9:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
ASPARTIC ACID
MEMBRANE TRANSPORT
CELL NUCLEI
NERVE CELLS
RATS
SURVIVAL TIME
TRACER TECHNIQUES
TRITIUM COMPOUNDS
VESTIBULAR APPARATUS
AMINO ACIDS
ANIMAL CELLS
ANIMALS
BODY
CARBOXYLIC ACIDS
CELL CONSTITUENTS
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
MAMMALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
RODENTS
SENSE ORGANS
SOMATIC CELLS
VERTEBRATES
551001* - Physiological Systems- Tracer Techniques
ASPARTIC ACID
MEMBRANE TRANSPORT
CELL NUCLEI
NERVE CELLS
RATS
SURVIVAL TIME
TRACER TECHNIQUES
TRITIUM COMPOUNDS
VESTIBULAR APPARATUS
AMINO ACIDS
ANIMAL CELLS
ANIMALS
BODY
CARBOXYLIC ACIDS
CELL CONSTITUENTS
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
MAMMALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
RODENTS
SENSE ORGANS
SOMATIC CELLS
VERTEBRATES
551001* - Physiological Systems- Tracer Techniques