Preoperative radiation therapy in endometrial carcinoma: preliminary report of a clinical trial. [Gamma radiation, linear accelerators, intracavitary irradiation]
Conference
·
· Am. J. Roentgenol.; (United States)
OSTI ID:7151720
A total of 91 patients with stage 1 endometrial adenocarcinoma who were referred for radiation prior to hysterectomy were randomly allocated to receive either intracavitary or external beam irradiation. Total abdominal hysterectomy was done 4--8 weeks later. The 53 patients who received intracavitary irradiation had an actuarial 5 year disease-free survival rate of 75 percent; the survival rate of the 38 patients in the external beam group was 48 percent. Nine patients in the external beam group had recurrence or metastases compared to two in the intracavitary group. These recurrences were predominantly pelvic. Complications were also more frequent in the external beam group. These results demonstrate that intracavitary radiation is superior to external beam radiation using the regimens described.
- Research Organization:
- Univ. of Illinois, Peoria
- OSTI ID:
- 7151720
- Conference Information:
- Journal Name: Am. J. Roentgenol.; (United States) Journal Volume: 127:2
- Country of Publication:
- United States
- Language:
- English
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ACCELERATORS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
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FEMALE GENITALS
GAMMA RADIATION
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IONIZING RADIATIONS
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ORGANS
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RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIATIONS
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RADIOTHERAPY
SURGERY
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