Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Hepatic uptake of technetium-99m diphosphonate in thalassemia major

Journal Article · · Clin. Nucl. Med.; (United States)
Two cases of thalassemia major are presented in which bone scintigraphy demonstrated diffuse hepatic uptake of Tc-99m diphosphonate. Although abnormal splenic and renal uptake of Tc-99m phosphates has been reported in patients with thalassemia major, hepatic uptake has not been reported previously. This scintigraphic finding is presumably due to increased iron deposition in the liver, resulting from increased iron turnover and retention in these patients and from multiple previous blood transfusions.
Research Organization:
Columbia-Presbyterian Medical Center, New York, NY
OSTI ID:
7134195
Journal Information:
Clin. Nucl. Med.; (United States), Journal Name: Clin. Nucl. Med.; (United States) Vol. 2; ISSN CNMED
Country of Publication:
United States
Language:
English