Metabolism in rats of selenium from intrinsically and extrinsically labeled isolated soy protein

Journal Article · Wed Oct 01 00:00:00 EDT 1986 · J. Nutr.; (United States)

OSTI ID:7132521

Mason, A C; Weaver, C M

Absorption, retention and tissue accumulation by rats of /sup 75/Se from intrinsically labeled isolated soy protein were compared with utilization of /sup 75/Se from the extrinsic sources of (/sup 75/Se)selenite, (/sup 75/Se)selenate or (/sup 75/Se)selenomethionine. Extrinsic sources of selenium were given by gavage or mixed with isolated soy protein. There were no differences in absorption and retention of /sup 75/Se from intrinsically labeled soy diet compared to the three extrinsically labeled soy diets. Of the three extrinsic sources tested, /sup 75/Se from selenate was better absorbed than from selenite or selenomethionine when incorporated into a soy diet. Absorption of /sup 75/Se was significantly lower when given to animals in gavage solution than when mixed with soy diets. After a 14-d test period, retention of /sup 75/Se was the same for all four soy diet groups. In gavaged groups, /sup 75/Se from selenomethionine was retained to a greater extent than /sup 75/Se from selenite. The liver, testes and kidney accumulated more /sup 75/Se from the test meal than did the blood and lungs. In the testes more /sup 75/Se from selenite and selenate was accumulated than from selenomethionine-labeled diets. Selenium absorption from the soy isolate source was very high (86-96%), indicating that, although soy does not normally contain high levels of selenium, the selenium present is well absorbed from this plant source.

• Research Organization: Purdue Univ., West Lafayette, IN
• OSTI ID: 7132521
• Journal Information: J. Nutr.; (United States), Vol. 10
• Country of Publication: United States
• Language: English

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SELENIUM 75
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