Selenium in soybeans: bioavailability and form

Thesis/Dissertation · Sun Jan 01 00:00:00 EST 1984

OSTI ID:5775888

Mason, A C

Experiments are presented which evaluate the bioavailability of different forms of selenium from intrinsically and extrinsically labeled isolated soy protein and soy flour. The bioavailability of selenium from soy and egg is compared and some characteristics of selenium are described as it exists in soybeans. The metabolism of selenium was measured by whole-body and tissue radioactivity retention and selenium excretion. Selenium-75 was well absorbed from an isolated soy protein diet by rats. Selenium-75 from isolated soy protein labeled intrinsically and extrinsically with /sup 75/Se selenate was better absorbed than from protein labeled extrinsically with /sup 75/Se selenite or /sup 75/Se selenomethionine. Bioavailability of selenium from soy flour and egg was measured by whole-body and tissue radioactivity retention and glutathione peroxidase (GSH-Px) activity regeneration. Selenium-75 from soy flour intrinsically labeled with selenite was better absorbed than /sup 75/Se from flour intrinsically labeled with selenate. GSH-Px levels in the liver, kidney, platelets and heart fell when rats were fed a selenium deficient diet, but were not significantly raised on 0.0825 ppm Se repletion diets.

• Research Organization: Purdue Univ., Lafayette, IN (USA)
• OSTI ID: 5775888
• Resource Relation: Other Information: Thesis (Ph. D.)
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
PEROXIDASES
ENZYME ACTIVITY
SELENIUM
BIOLOGICAL AVAILABILITY
METABOLISM
DIET
EGGS
EXCRETION
GLUTATHIONE
LABELLED COMPOUNDS
RATS
RETENTION
SELENATES
SELENITES
SELENIUM 75
SOYBEANS
TRACER TECHNIQUES
ANIMALS
BETA DECAY RADIOISOTOPES
CARBOXYLIC ACIDS
CLEARANCE
DAYS LIVING RADIOISOTOPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
ENZYMES
EVEN-ODD NUCLEI
FOOD
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OXIDOREDUCTASES
OXYGEN COMPOUNDS
PEPTIDES
PLANTS
POLYPEPTIDES
PORPHYRINS
PROTEINS
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES
RODENTS
SELENIUM COMPOUNDS
SELENIUM ISOTOPES
SEMIMETALS
VEGETABLES
VERTEBRATES
560303* - Chemicals Metabolism & Toxicology- Plants- (-1987)
560305 - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
550501 - Metabolism- Tracer Techniques