Blink reflex latency after exposure to trichloroethylene in well water

Journal Article · Tue Mar 01 00:00:00 EST 1988 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1988.9935843· OSTI ID:7125390

Feldman, R G; Chirico-Post, J; Proctor, S P

The electrophysiological measurement of the blink reflex (BR) can quantify the conduction latency in the reflex arc involving the Vth (trigeminal) and VIIth (facial) cranial nerves. We measured the electrophysiological BR in a population (N = 21), which had alleged chronic exposure to trichloroethylene (TCE) through the public drinking water at levels 30-80 times higher than the Environmental Protection Agency (EPA) Maximum Contamination Level (MCL). A highly significant difference was observed in the conduction latency means of the BR components (p less than .0001), when the study population was compared with laboratory controls (N = 27). This difference suggests a subclinical alteration of the Vth cranial nerve function due to chronic, environmental exposure to TCE.

• Research Organization: Boston Univ. School of Public Health, MA (USA)
• OSTI ID: 7125390
• Journal Information: Arch. Environ. Health; (United States), Vol. 43:2
• Country of Publication: United States
• Language: English

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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CHLORINATED ALIPHATIC HYDROCARBONS
TOXICITY
DRINKING WATER
CONTAMINATION
NERVES
SENSITIVITY
CHRONIC EXPOSURE
ELECTROPHYSIOLOGY
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NERVOUS SYSTEM
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ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
OXYGEN COMPOUNDS
PHYSIOLOGY
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SAFETY STANDARDS
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WATER
560300* - Chemicals Metabolism & Toxicology