Translation of messenger RNS specific for tyrosine aminotransferase in oocytes of Xenopus laevis

Journal Article · Wed Dec 31 23:00:00 EST 1975 · Biochem. Biophys. Res. Commun.; (United States)

DOI:https://doi.org/10.1016/S0006-291X(76)80094-0· OSTI ID:7124640

Nickol, J M; Lee, K L; Hollinger, T G; Kenney, F T

Injection of rat liver polysomal poly(A)-containing RNA into oocytes of Xenopus laevis results in synthesis of a protein whose immunochemical and electrophoretic characteristics are identical to liver tyrosine aminotransferase. Poly(A)-RNA from hydrocortisone-treated rat liver stimulates about five times more aminotransferase synthesis than does poly(A)-RNA from controls, establishing that the steroid hormone increases the level of functional hepatic tyrosine aminotransferase mRNA.

• Research Organization: Oak Ridge National Lab., TN
• OSTI ID: 7124640
• Journal Information: Biochem. Biophys. Res. Commun.; (United States), Journal Name: Biochem. Biophys. Res. Commun.; (United States) Vol. 72:2; ISSN BBRCA
• Country of Publication: United States
• Language: English

Related Subjects

551000* -- Physiological Systems
59 BASIC BIOLOGICAL SCIENCES
ADRENAL HORMONES
AMINOTRANSFERASES
AMPHIBIANS
ANIMALS
AQUATIC ORGANISMS
BIOSYNTHESIS
BODY
CORTICOSTEROIDS
DIGESTIVE SYSTEM
ENZYMES
FROGS
GERM CELLS
GLANDS
GLUCOCORTICOIDS
HORMONES
HYDROCORTISONE
HYDROXY COMPOUNDS
KETONES
LIVER
MESSENGER-RNA
NUCLEIC ACIDS
OOCYTES
ORGANIC COMPOUNDS
ORGANS
PREGNANES
PROTEINS
RNA
STEROID HORMONES
STEROIDS
SYNTHESIS
TRANSFERASES
VERTEBRATES