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Cancellous-marrow bone grafts in irradiated tissue

Journal Article · · Oral Surg., Oral Med., Oral Pathol.; (United States)

Discontinuity defects of the mandible have been successfully treated by means of cancellous-marrow grafting techniques. This method of reconstruction has not been widely reported in the repair of defects in mandibles that have been exposed to radiation therapy. In the two cases presented in this article, the patients were previously treated for oral squamous-cell carcinoma by irradiation and partial mandibulectomy. Later, cancellous-marrow grafts were implanted. One patient received 3,000 rads of /sup 60/Co and had the body of the right mandible resected. The subsequent grafting procedure was successful in this patient. The second patient received 6,000 rads of /sup 60/Co and underwent resection of the mandible anterior to the molar region. The subsequent graft failed in this case.

Research Organization:
Veterans Administration Hospital, Lexington, KY
OSTI ID:
7120504
Journal Information:
Oral Surg., Oral Med., Oral Pathol.; (United States), Journal Name: Oral Surg., Oral Med., Oral Pathol.; (United States) Vol. 42:4; ISSN OSOMA
Country of Publication:
United States
Language:
English