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Xenon-127, a comparison with xenon-133 for ventilation studies

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:7116106
;
In /sup 133/Xe ventilation studies the 81-keV gamma photon emitted is a major disadvantage for imaging. Using a lung model with the same attenuation coefficient as inflated lung, we compared /sup 133/Xe with /sup 127/Xe to determine the smallest ''lesion'' that could be imaged at different places within the lung. With the ''lung lesion'' directly against the collimator, the lesion had to be 10 ml in volume in order to be seen with /sup 127/Xe, but with /sup 144/Xe the ''lesion'' had to be 30 ml. Xenon-127 gave better resolution, no matter where the lesion was placed within the lung. Xenon-127 was not better than /sup 133/Xe in resolving a lead bar phantom. When /sup 133/Xe was used with /sup 99m/Tc in a model of pulmonary embolism, a ''ventilation defect'' was apparent even though the distribution of xenon was even throughout the model. This artifact was not seen when the /sup 127/Xe model was imaged.
Research Organization:
McMaster Univ., Hamilton, Ont.
OSTI ID:
7116106
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 18:3; ISSN JNMEA
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
IMAGES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LUNGS
MOCKUP
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PHANTOMS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATION
RESPIRATORY SYSTEM
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
STRUCTURAL MODELS
TECHNETIUM 99
TECHNETIUM ISOTOPES
XENON 127
XENON 133
XENON ISOTOPES
YEARS LIVING RADIOISOTOPES